I presented a populace-oriented, prospective cohort investigation to examine this new connections anywhere between personality traits and malignant tumors chance and success. Based on early in the day degree, we requested you to definitely numerous activities play a role from the causal pathway ranging from character traits and you can cancer chance and you may emergency. In particular, i expected one lots of lifestyle facts (elizabeth.grams., smoking and you can alcohol consumption) get become mediators and thus the effectation of identity qualities work using such affairs and never separately. Towards good the knowledge, ours is the largest examination of the fresh connection anywhere between characteristics and you may disease exposure and endurance.
The present day data is actually centered on combined research out-of Finnish and you may Swedish dual cohorts. This type of investigation were information about character traits and you will information on existence factors; to start with, the data for both nations should be connected with registry information for the disease and essential status. So it compilation of information thus even offers another chance for examining characteristics and you will cancers chance and you will endurance.
The brand new Finnish twin cohort could have been examined for the a large, possible, population-founded research ( 22). The brand new cohort users were delivered forms plus facts towards the character traits inside the 1975 and you will 1981, however, i used singular-go out dimension off characteristics (1975 survey) since they’re regarded as secure into the adulthood ( 23). We integrated twins and you will singletons who came across the option requirements and you will whom responded to the standard questionnaire during the 1975 (letter = 31,145).
The fresh Swedish twin cohort is recognized throughout the society-situated Swedish Dual Registry, the largest of their kind internationally, which includes details about more 140,100 twins ( 24). The fresh registry contains research for step 3 cohorts, spanning twins born ranging from 1886 and 1925, twins born anywhere between 1926 and you can 1958, and you will twins born anywhere between 1959 and you may 1990. We used study towards the 36,536 persons in-between cohort just who responded to set up a baseline survey sent in 1973.
We put an enthusiastic abbreviated style of the fresh Eysenck Character List (EPI-Q), that is a preliminary sorts of the brand new Eysenck Identity Collection (EPI Means B). Whenever a past study created the dos proportions, most of the circumstances was indeed chose on high pool of EPI things according to the capacity to differentiate between the upper minimizing catalog rating quartiles getting 400 nontwins ( 25). EPI-Q lets aspect away from 2 size of personality: extraversion and you will neuroticism ( 23, 26). Both in the new Finnish and you may Swedish sizes, extraversion is reviewed having nine circumstances (you can easily score range, 0–9); neuroticism was analyzed which have 10 facts (you can easily score diversity, 0–10) on the Finnish adaptation with nine affairs (it is possible to variety, 0–9) from the Swedish variation. The fresh new neuroticism item, Have you got problems within the dropping off to sleep?, sprawdziД‡ tД™ witrynД™ was not within the Swedish adaptation. With the each other balances, high score indicate an increased habit of feel the personality characteristic. Extraversion means sociability and liveliness, while neuroticism means psychological imbalance and you can anxieties ( 27).
I gotten one to-go out tips off identified otherwise thought cancer risk circumstances within standard assessments during the 1973 when you look at the Sweden and 1975 inside Finland. Believed have been studies, parity, weight, top, and existence situations, along with puffing condition and you will alcohol consumption.
Information on cancer tumors diagnoses is actually gotten from the number linkage to the national cancer tumors registries into the Finland and you may Sweden utilizing the unique personality number assigned to anyone staying in those places. The new Finnish Malignant tumors Registry keeps information on all instances of cancer tumors identified within the Finland because 1953 ( 28); this new Swedish Cancers Registry keeps information about cancer diagnosed within the Sweden since 1958 ( 29). Into the current analysis, tumefaction morphology is according to research by the Around the globe Class off Disease, 7th Revise. Studies into the emigration and you may dying was basically gotten within the Finland because of the checklist linkage to your Populace Register Hub plus Sweden by the listing linkage into National Populace Register.
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